CV Luis Martí-Bonmati

Luis Martí BonmatíLuis Martí Bonmatí

ORCID: 0000-0002-8234-010X
Scopus ID: 55259609700
Researcher ID: A-1147-2015
Date of birth: 30/12/1959
Nationality: Spain. Country of birth: Spain
Aut. region/reg. of birth: Valencian Community. Contact province: Valencia
Position Title: Director Medical Imaging Clinical Unit. Chairman Department of the Radiology Department and of the Biomedical Imaging Research Group (GIBI230).
La Fe University and Polytechnic Hospital and La Fe Health Research Institute. 46026 Valencia.
Contact country: Spain
Contact aut. region/reg.: Valencian Community
Contact e-mail: marti_lui@gva.es

Personal Statement

After graduating in Medicine (University of Valencia, 1978-1983) with the Extraordinary Graduation Award, and completing his postgraduate training as a resident in Radiology (1984-1987), Dr. Martí-Bonmatí obtained his Doctoral Thesis (PhD) with his work on Magnetic Resonance imaging in liver tumors (Cum Laude, 1991), obtaining the Extraordinary University Award (1991).

In 1987 he became Radiology Staff in the first University Hospital Radiology Depatment with an MR system in Spain (Dr. Peset University Hospital, Valencia). In 1995, he became Section Chief of Magnetic Resonance Imaging in this Radiology Department. Since 1997 he also serves as Head of the Radiology Department at Quirónsalud Hospital in Valencia, integrating biomedical engineering in the radiological innovation process in that center.

In 2009, Dr. Martí-Bonmatí became Chairman of the Radiology Department and Director of the Medical Imaging Department at La Fe University and Polytechnic Hospital, Valencia. This hospital is the reference center for advance treatments and complex diseases within the Valencia Community.

That same year he was designated as Radiology coordinator of the Catholic University in Valencia, and in 2011 became Professor of Radiology and supervisor at the University of Valencia. He has been up to now the Director of 49 Doctoral Thesis and End of Career Projects.

In relation to his academic activities, mention should be made of his nomination as full academic member of the Spanish Royal National Academy of Medicine (2015, in representation of Radiology). He is also Honorary member of the Royal Academy of Medicine of the Valencian Community (2017).

Since 2012, Dr. Marti-Bonmatí has been the founder and Director of the Research Group on Biomedical Imaging (GIBI230) within La Fe Health Research Institute, a center belonging to the Spanish Research Network at the Spanish Ministry of Science and Technology. The group focuses on radiomics, imaging biomarkers and structured reporting, having a large interest also in preclinical animal imaging and calibration experiments. This group has close stablish collaborations with other research groups within the Valencia University and the Polytechnic University of Valencia.

He has co-founded QUIBIM (Quantitative Imaging Biomarkers in Medicine, QUIBIM), an innovative spin-off company from the Research Institute dedicated to medical image processing, analysis, extraction and measurement of radiomic data and imaging biomarkers to be used in clinical diagnostics, research projects and clinical trials. The group is now constituted by 12 biomedical engineers, working closely with those researchers within the Research Group on Biomedical Imaging.

His collaboration with different Spanish Biomedical Data Science Lab (IBIME), Institute of Applications of Information Technology and Advanced Communications (ITACA), Institute of Instrumentation for Molecular Imaging (I3M), European research institutes (European Institute for Biomedical Imaging Research (EIBIR), European Imaging Biomarkers Alliance (EIBALL) and Euro-BioImaging, facilitates joint research efforts in very diverse fields. Such collaboration significantly improves the development and validation of imaging biomarkers. Some examples of static or structural biomarkers are brain cortical thickness, neuronal density of the cortex, white substance volumetry, and concrete brain areas such as the hippocampus or injuries caused by multiple sclerosis. The candidate has also worked in the evaluation of myocardial density and the quantification of wall fibrosis. Liver segmentation volumetry, the quantification of emphysema and pulmonary vascularization, joint cartilage thickness, and the microstructure, rigidity and fragility of the trabecular bone have also been the subject of study by his group. Volumes, topological parameters and fractal dimensions are standard areas in his work with these structural biomarkers.

He is a member of the Spanish National Radiology Commission (since 2014) to advice the Spanish Ministry of Health in specialty advanced education.

Positions and Honors

Dr. Martí-Bonmatí has been President of the following societies:

  • European Society of Magnetic Resonance in Medicine and Biology (ESMRMB, 2002-2004, Honorary Fellow 2010)
  • Spanish Society of Radiology (SERAM, 2008-2010, being awarded Gold Medal in 2014)
  • Spanish Society of Abdominal Radiology (SEDIA, 2000-2007, Founder and Editor of its journal, Radiología Abdominal from 2004-2013)
  • European Society of Gastrointestinal and Abdominal Radiology (ESGAR, 2013-2015, being awarded Gold Medal in 2018).
  • Spanish School of Clinical Magnetic Resonance and Computer Tomography (ESRMCTC, 2006-2012)

He is also Honorary Fellow of the the Asian Society of Abdominal Radiology (ASAR, 2015) and Honorary Member of the Portuguese Society of Radiology and Nuclear Medicine (2015). fellow of the International Cancer Imaging Society (ICIS, 2011). He is also Fellow of the International Cancer Imaging Society (ICIS, 2011).

Dr. Martí-Bonmatí has been the President of the SERAM Annual Meeting Scientific Committee in 2008 (Coruña) and he has also served as ESGAR President of the Annual Meeting Scientific Committee for Prague and Athens (2016-2017).

He has been Founder and Director of the Association for the Development and Investigation of Medical Radiology (ADIRM, since 2005), a non-profit institution developed to enhance the development of medical imaging by using local universities and research groups resources.

Dr. Marti-Bonmati has been a member of the Executive Council and has served as Director of the Research Committee of the European Society of Radiology (ESR, 2010-2013), starting the Imaging Biomarkers Subcommittee, and representing Radiology in the European Council for Health Research at the Alliance for Biomedical Research in Europe (biomedeurope.org).

He has given the Honorary Lecture at the Society of Gastrointestinal Radiology (Orlando, Florida 2010) and at the European Congress of Radiology “Ramón y Cajal” Honorary Lecture on “Research and science: from individuals to societies” (2013) in recognition of his research activity.

The candidate is a lecturer and course organizer of the European Magnetic Resonance School of Magnetic Resonance Imaging in Medicine and Biology (1997-2005) and of the European School of Radiology (2000 since now), acting a member of its Steering Committee since 2015.

He has been a member of the Council and General Secretary of the International Society of Radiology (2014 to 2016). He is also member of the Economic Committee (since 2013) and Regional Europe Committee (since 2016) of the Radiological Society of North America.

In 2008, Dr. Martí-Bonmatí has received the European Magnetic Resonance Award of the European Magnetic Resonance Forum (EMRF) for his investigations in MRI. He has also received the Pro-Academia Prize in 2013 for “Exemplary group in Science and Academic life” of the Round Table Foundation and the European Magnetic Resonance Forum. In 2014 he was awarded the Teleco Honoris Causa Prize from the Official College of Telecommunications Engineers of the Valencian Community.

He belongs to the Patronage of the Oceanography Fyundation (since 2016).
He has received an Honorary Degree Doctorate Distinction from the National University of Tucumán, Argentina (2015).

Contributions to science

Dr. Martí-Bonmatí has been Associate Editor of European Radiology (Magnetic Resonance) and Radiology (Computer Applications). He has also been a member of the Editorial Board of the journals Cancer Imaging and Diagnostic Imaging Europe. He is currently the Editor-in-Chief of Insights into Imaging.

Dr. Martí-Bonmatí is the author of over 585 publications. The most relevant publications in his carrier are:

  1. Marti-Bonmati L, Ruiz Perales F, Catala F, Mata JM, Calonge E. CT findings in Swyer-James syndrome. Radiology. 1989 Aug;172(2):477-80. PubMed PMID: 2748829.
  2. Martí-Bonmatí L, Menor F, Poyatos C, Cortina H. Diagnosis of Sturge-Weber syndrome: comparison of the efficacy of CT and MR imaging in 14 cases. AJR Am J Roentgenol. 1992 Apr;158(4):867-71. PubMed PMID: 1546607.
  3. Martí-Bonmatí L, Talens A, del Olmo J, de Val A, Serra MA, Rodrigo JM, Ferrández A, Torres V, Rayón M, Vilar JS. Chronic hepatitis and cirrhosis: evaluation by means of MR imaging with histologic correlation. Radiology. 1993Jul;188(1):37-43. PubMed PMID: 8511317.
  4. Martí-Bonmatí L, Masiá L, Torrijo C, Casillas C, Ferrer MD. Dynamic MR imaging of liver tumors: analysis with temporal reconstruction images. Radiology. 1994 Dec;193(3):677-82. PubMed PMID: 7972807.
  5. Martí-Bonmatí L, Masiá L, Casillas C, Ronchera-Oms CL, Torrijo C. Differentiation of healthy from cirrhotic livers. Evaluation of parametric images after contrast administration in magnetic resonance imaging. Invest Radiol. 1996 Dec;31(12):768-73. PubMed PMID: 8970879.
  6. Martí-Bonmatí L, Lull JJ, García-Martí G, Aguilar EJ, Moratal-Pérez D, Poyatos C, Robles M, Sanjuán J. Chronic auditory hallucinations in schizophrenic patients: MR analysis of the coincidence between functional and morphologic abnormalities. Radiology. 2007 Aug;244(2):549-56. PubMed PMID: 17641373.
  7. Martí-Bonmatí L, Alberich-Bayarri A, Sánchez-González J. Overload hepatitides: quanti-qualitative analysis. Abdom Imaging. 2012 Apr;37(2):180-7. PubMed PMID: 21643735.
  8. Martí-Bonmatí L, Ramirez-Fuentes C, Alberich-Bayarri Á, Ruiz-Llorca C. State-of-the-art of bone marrow imaging in multiple myeloma. Curr Opin Oncol. 2015 Nov;27(6):540-50. PubMed PMID: 26352540.
  9. Juan-Albarracín J, Fuster-Garcia E, Pérez-Girbés A, Aparici-Robles F, Alberich-Bayarri Á, Revert-Ventura A, Martí-Bonmatí L, García-Gómez JM. Glioblastoma: Vascular Habitats Detected at Preoperative Dynamic Susceptibility-weighted Contrast-enhanced Perfusion MR Imaging Predict Survival. Radiology. 2018 Jan 19:170845. doi: 10.1148/radiol.2017170845. [Epub ahead of print] PubMed PMID: 29357274.
  10. Carles M, Bach T, Torres-Espallardo I, Baltas D, Nestle U, Martí-Bonmatí L. Significance of the impact of motion compensation on the variability of PET image features. Phys Med Biol. 2018 Feb 22. doi: 10.1088/1361-6560/aab180.

He is Editor of 9 books, and the author of 55 book chapters such as:

  1. Martí-Bonmatí L; Alberich-Bayarri A. Imaging Biomarkers. Development and Clinical Integration. pp. 1 – 306. (Switzerland): Springer, 2016. ISBN 978-3-319-43502-2
  2. Martí-Bonmatí L; Alberich-Bayarri A; García Castro F. Imaging Biomarkers and personalized medicine: need for validation. 314424 – Nuclear España. pp. 2 – 7. (Spain): Senda Editorial S.A., 2016. ISSN 1137-2885
  3. França M; Alberich-Bayarri A; Martí-Bonmatí L. Diffuse liver disorders: imaging detection and quantification. Avances en Imagen Hepática. 1, pp. 7 – 29. Madrid(Spain): Aran Ediciones S.L, 2016. ISBN 2530-0342
  4. Martí-Bonmatí L. Introduction to the stepwise development of imaging biomarkers. Imaging Biomarkers. Development and clinical integration. pp. 9 – 28. (Switzerland): Springer, 2016. ISBN 978-3-319-43502-2
  5. Ruiz-Martinez E; Segrelles Quilis JD; García Castro F; Martí-Bonmatí L; Alberich-Bayarri A. The Final step: imaging biomarkers in structured reports. Imaging Biomarkers. Development and clinical integration. pp. 123 – 138. (Switzerland): Springer, 2016. ISBN 978-3-319-43502-2
  6. França M; Alberich-Bayarri A; Martí-Bonmatí L. Use Case VI: imaging biomarkers in diffuse liver disease. Quantification of fat and iron. Imaging Biomarkers. Development and clinical integration. pp. 279 – 294. (Switzerland): Springer, 2016. ISBN 978-3-319-43502-2
  7. Pedraza S; Martí-Bonmatí L. Research in a Radiology Service. Radiology research. pp. 11 – 17. (Spain): L&C Diseño SL, 2014. ISBN 978-84-941730-2-8
  8. Martí-Bonmatí L; Alberich-Bayarri A; García-Martí G; Sanz-Requena R. Multiparametric Imaging. Functional Imaging in Oncology. pp. 523 – 536. Berlin Heidelberg(Germany): Springer-Verlag, 2014. ISBN 978-3-642-40411-5
  9. de la Iglesia-Vaya M.; Molina-Mateo J.; Escarti-Fabra MJ.; Kanaan AS.; Martí-Bonmatí L. Brain Connections – resting state fMRI functional connectivity.Novel Frontiers of advanced neuroimaging. pp. 51 – 66. (Croatia): InTech- Open Access Publisher, 2013. ISBN 978-953-51-0923-5

Most of his publications and books are focused on Magnetic Resonance, Clinical Radiology, the development of Imaging Biomarkers, and Engineering-supported Biomedical Research.
He holds 10 patents and software registries in exploitation. Some examples are:

  1. Automated method for quantification and quality control in computed tomography (nº of patent: V-900-14)
  2. Software for optimizing parameters in perfusion studies with ultrasound tomography (nº of patent: V-902-14)
  3. Variable adaptive threshold segmentation method for obtaining air reference values in imaging studies by computed tomography (nº of application: P201331295)
  4. Procedure for the Calculation of a Degeneration Index of Cartilage (nº of application: P201231727)

The candidate has actively participated in 33 financed research projects, with a global budget of more than 51,8 million €. He has been the Principal Investigator in 14 of these projects, with a total financial support of 42,1 million €.

Some examples of these funding projects are:

  1. Name of the project: “CVREMOD (Gestión de remodelado cardiovascular mediante interacción de tecnologías de monitorización ubicua y conceptos del humano fisiológico virtual)”.
    Principal researcher: Luis Marti Bonmati
    CENIT-E 2009 (quinta convocatoria del Programa de Consorcios Estratégicos Nacionales en Investigación Técnica del Plan Nacional de I+D+i 2008-2011) del Ministerio de Ciencia e Innovación.
    Total amount: 31.911.458 €- Duration: 3 years – 3 months – 16 days
  2. Name of the project: Cardiorespiratory physiology in the bottlenosedolphin before and after breath-holding and exercise.
    Name principal researcher: Luis Marti Bonmati
    Funding entity or bodies: OFFICE OF NAVAL RESEARCH
    Total amount: 282.646,56 € – Duration: 3 years
  3. Name of the project: Brain repair after stroke: magnetic field-mediated stem cell
    Principal researcher: Luis Marti Bonmati
    Funding entity or bodies: Fundació La Marató de TV3
    Total amount: 305.675 € Duration: 3 year
  4. Name of the project: Cuantificación de la Inflamación, grasa, hierro y fibrosis mediante biomarcadores de imagen de RM en pacientes trasplantados hepáticos con infección recurrente por virus de hepatitis C.
    Principal researcher: Luis Martí-Bonmatí
    Funding entity or bodies: Ministerio de Economía y Competitividad
    Total amount: 19.965 € Duration: 3 years
  5. Name of the Project: COCO-CLOUD: Confidential and Compliant Clouds.
    Name principal researcher: Luis Marti-Bonmati
    Funding entity or bodies: European Commission.
    Budget: 4.700.000€ Duration: 3 years
  6. Name of the Project: Euro-Bioimaging: Empowering Europe to lead the revolution in imaging technologies. European Commission.
    Principal researcher: Luis Marti Bonmati
    Budget: open € Duration: open
  7. Name of the Project: Imaging-La Fe: Infraestructuras Científico Técnicas Singulares.
    Principal researcher: Luis Marti Bonmati
    Funding entity or bodies: Ministerio de Ciencia, Innovación y Universidades
    Budget: 5.100.000 € Duration: open
  8. Name of the Project: PRIMAGE: PRedictive In-silico Multiscale Analytics to support cancer personalized diaGnosis and prognosis, Empowered by imaging biomarkers (SC1-DTH-07-2018 (RIA))
    Principal researcher: Luis Marti Bonmati (Coordinator)
    Funding entity or bodies: European Commission.
    Budget: 10.000.000 € Duration: 2018-2022

Dr. Marti Bonmati has led several Research and Develop projects with private entities:

  1. Name of the project: Development of a predictive model of effectiveness for the implantation of electrical neurostimulators in patients with chronic pain using biomarkers extracted from magnetic resonance.
    Principal researcher: Luis Marti Bonmati
    Funding entity or bodies: Boston Scientific Iberica, S.A.
    Total amount: 129.833 € – Duration: 3 years
  2. Name of the project: Integration of prognostic imaging biomarkers for the in silico Magnetic Resonance phenotyping and staging of endometrial cancer.
    Principal researcher: Luis Marti Bonmati
    Funding entity or bodies: Bracco S.P.A.
    Total amount: 40.000 € Duration: 2 years
  3. Name of the project: Unsupervised glioblastoma tumor components segmentation based on perfusión multiparametric MRI and spatial/temporal constraints
    Principal researcher: Luis Marti Bonmati
    Funding entity or bodies: Bracco S.P.A.
    Total amount: 40.000 € Duration: 2 years
  4. Name of the project: Experimental Radiology Platform and Imaging Biomarkers
    Principal researcher: Luis Marti Bonmati
    Funding entity or bodies: Philips Ibérica, S.A.
    Total amount: 70.000 € Duration: 5 years

Dr. Martí-Bonmatí has a Hirsch h-index between 31 and 42 (31 web of Science, of 37 (Research Gate, 03-2018). The mean ratio is 11,51 citations per article (Web of Science Researcher ID, 03-2018). His Research Gate Score is 44,98 (97.5% percentile Research members, 03-2018). His i10 index is 137 (Google Scholar, 06-2018).
His special areas of interest are mainly imaging biomarkers, image processing, imaging biobanks, and clinical innovations in medical imaging.